hsa miR miRNA Inhibitor ABM

hsa miR miRNA Inhibitor ABM

Background

Non-coding RNAs and significantly microRNAs have been discovered to behave as grasp regulators of most cancers initiation and improvement. The intention of our analysis was to seek out and characterize the carry out of however functionally uncharacterized microRNAs in human breast carcinogenesis.

miRNA inhibitors block miRNA regulation of purpose gene expression by safe suppression and may knock down native miRNA expression in cells. They are often utilized in miRNA loss-of-function analysis, miRNA purpose site identification and validation, and miRNA screening experiments. abm‘s Lentivirus miRNA Inhibitors allow for safe, long term expression of miRNA inhibitors out of your cell line.

Key Choices

  • We offer a gaggle of miRNA Inhibitors for knockdown of over 5000 miRNAs from human, mouse, and rat.
  • Lentiviral provide for integration of genetic supplies into host cells, inflicting safe, long term gene expression.
  • Lentivirus has a broad host differ and may infect every dividing and non-dividing cells, allowing gene provide to every kind of cell types.

For gene regulation and helpful analysis, abm presents a variety of expression strategies for:

  1. siRNA: successfully categorical any purpose siRNA to knockdown any gene with out the need to design hair-pin loop shRNA constructions, obtainable in lentivirus, AAV and Adenovirus.
  2. miRNA: inhibit or over-express any miRNA for analysis of post-transcriptional gene regulation in mammalian strategies using our ready-to-use viral vectors and packaged viruses, along with our detection and quantification devices.
  3. UTR Reporters: quantitatively analysis a specific miRNA’s regulation of its purpose gene using our 3’UTR or 5’UTR platform, all obtainable as a library of premade lentiviral vectors and lentiviruses for any human, mouse or rat gene.
abm hsa mirna inhibitor
abm hsa mirna inhibitor

 

Methods

In an unbiased technique, we utilized a longtime model system for breast most cancers (BC) stem cell formation (“mammosphere assay”) to determine full miRNome alterations in breast carcinogenesis. Medical samples of BC victims had been used to guage the human relevance of the newly acknowledged miRNA candidates. One promising candidate, miR-1287-5p, was further explored on its impression on quite a lot of hallmarks of most cancers. The molecular mode of movement was characterised by full transcriptome analysis, in silico prediction devices, miRNA-interaction assays, pheno-copy assays, and drug sensitivity assays.

hsa-miR-95 miRNA Inhibitor

MIH03958 2 x 5.0 nmol
EUR 211.2

hsa-miR-96 miRNA Inhibitor

MIH03963 2 x 5.0 nmol
EUR 211.2

hsa-miR-98 miRNA Inhibitor

MIH03966 2 x 5.0 nmol
EUR 211.2

hsa-miR-16 miRNA Inhibitor

MIH01377 2 x 5.0 nmol
EUR 211.2

hsa-miR-17 miRNA Inhibitor

MIH01381 2 x 5.0 nmol
EUR 211.2

hsa-miR-21 miRNA Inhibitor

MIH01533 2 x 5.0 nmol
EUR 211.2

hsa-miR-22 miRNA Inhibitor

MIH01581 2 x 5.0 nmol
EUR 211.2

hsa-miR-24 miRNA Inhibitor

MIH01615 2 x 5.0 nmol
EUR 211.2

hsa-miR-25 miRNA Inhibitor

MIH01621 2 x 5.0 nmol
EUR 211.2

hsa-miR-30* miRNA Inhibitor

MIH01661 2 x 5.0 nmol
EUR 211.2

hsa-miR-31 miRNA Inhibitor

MIH01705 2 x 5.0 nmol
EUR 211.2

hsa-miR-32 miRNA Inhibitor

MIH01853 2 x 5.0 nmol
EUR 211.2

hsa-miR-549 miRNA Inhibitor

MIH03054 2 x 5.0 nmol
EUR 211.2

hsa-miR-552 miRNA Inhibitor

MIH03067 2 x 5.0 nmol
EUR 211.2

hsa-miR-553 miRNA Inhibitor

MIH03070 2 x 5.0 nmol
EUR 211.2

hsa-miR-554 miRNA Inhibitor

MIH03071 2 x 5.0 nmol
EUR 211.2

hsa-miR-555 miRNA Inhibitor

MIH03072 2 x 5.0 nmol
EUR 211.2

hsa-miR-557 miRNA Inhibitor

MIH03075 2 x 5.0 nmol
EUR 211.2

hsa-miR-558 miRNA Inhibitor

MIH03078 2 x 5.0 nmol
EUR 211.2

hsa-miR-559 miRNA Inhibitor

MIH03099 2 x 5.0 nmol
EUR 211.2

hsa-miR-561 miRNA Inhibitor

MIH03104 2 x 5.0 nmol
EUR 211.2

hsa-miR-562 miRNA Inhibitor

MIH03107 2 x 5.0 nmol
EUR 211.2

hsa-miR-563 miRNA Inhibitor

MIH03108 2 x 5.0 nmol
EUR 211.2

hsa-miR-564 miRNA Inhibitor

MIH03109 2 x 5.0 nmol
EUR 211.2

hsa-miR-566 miRNA Inhibitor

MIH03110 2 x 5.0 nmol
EUR 211.2

hsa-miR-567 miRNA Inhibitor

MIH03111 2 x 5.0 nmol
EUR 211.2

hsa-miR-568 miRNA Inhibitor

MIH03112 2 x 5.0 nmol
EUR 211.2

hsa-miR-569 miRNA Inhibitor

MIH03123 2 x 5.0 nmol
EUR 211.2

hsa-miR-570 miRNA Inhibitor

MIH03137 2 x 5.0 nmol
EUR 211.2

hsa-miR-571 miRNA Inhibitor

MIH03149 2 x 5.0 nmol
EUR 211.2

hsa-miR-572 miRNA Inhibitor

MIH03150 2 x 5.0 nmol
EUR 211.2

hsa-miR-573 miRNA Inhibitor

MIH03151 2 x 5.0 nmol
EUR 211.2

hsa-miR-575 miRNA Inhibitor

MIH03155 2 x 5.0 nmol
EUR 211.2

hsa-miR-577 miRNA Inhibitor

MIH03158 2 x 5.0 nmol
EUR 211.2

hsa-miR-578 miRNA Inhibitor

MIH03159 2 x 5.0 nmol
EUR 211.2

hsa-miR-579 miRNA Inhibitor

MIH03161 2 x 5.0 nmol
EUR 211.2

hsa-miR-580 miRNA Inhibitor

MIH03164 2 x 5.0 nmol
EUR 211.2

hsa-miR-581 miRNA Inhibitor

MIH03167 2 x 5.0 nmol
EUR 211.2

hsa-miR-583 miRNA Inhibitor

MIH03170 2 x 5.0 nmol
EUR 211.2
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